Metalloenzyme-Mimicking Supramolecular Catalyst for Highly Active and Selective Intramolecular Alkyne Carboxylation
نویسندگان
چکیده
منابع مشابه
Metalloenzyme-mimicking supramolecular catalyst for highly active and selective intramolecular alkyne carboxylation.
Creation of synthetic catalysts with enzyme-like behavior is challenging despite strong interest in such systems. Extraction of tetrachloroaurate into the hydrophilic core of an interfacially cross-linked reverse micelle (ICRM) produced an artificial "metalloenzyme" with highly unusual catalytic properties. The ICRM pulled the substrate toward the catalytic metal, which converted it efficiently...
متن کاملDinuclear thiazolylidene copper complex as highly active catalyst for azid–alkyne cycloadditions
A dinuclear N-heterocyclic carbene (NHC) copper complex efficiently catalyzes azide-alkyne cycloaddition (CuAAC) "click" reactions. The ancillary ligand comprises two 4,5-dimethyl-1,3-thiazol-2-ylidene units and an ethylene linker. The three-step preparation of the complex from commercially available starting compounds is more straightforward and cost-efficient than that of the previously descr...
متن کاملSnCl4·5H2O: A Highly Efficient Catalyst for Hydration of Alkyne
SnCl4·5H2O is a highly efficient catalyst in the hydration of terminal alkynes that affords carbonyl compounds in high to good yields. Under the optimized reaction conditions, the moderate to excellent yields of corresponding ketones were obtained when the aromatic and aliphatic terminal alkynes were used as substrates. With using diphenylacetylene as an internal alkyne, the corresponding keton...
متن کاملHighly active copper-catalysts for azide-alkyne cycloaddition.
Bis-triphenylphosphano complexes of copper(I)-carboxylates serve as efficient catalysts for azide-alkyne cycloaddition. The triazole formation takes place straightforwardly at ambient temperature providing a wide variety of products with good yields in the presence of 0.005-0.05% catalyst.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 2014
ISSN: 0002-7863,1520-5126
DOI: 10.1021/ja501277j